If you are in the US, then Locality is referring to the city and Region is referring to the state. These fall under the Address structure of Schema. Written out as JSON-LD in an HTML script tag it would look like this:
<script type="application/ld+json">
{
"@context": "https://schema.org",
"@type": "CollegeOrUniversity",
"address": {
"@type": "PostalAddress",
"addressLocality": "Phoenix",
"addressRegion": "AZ",
"postalCode": "85021",
"streetAddress": "2233 W Dunlap Ave"
}
</script>
Read More: https://schema.org/addressRegion
